ORM1
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesORM1, AGP-A, AGP1, HEL-S-153w, ORM, orosomucoid 1
External IDsOMIM: 138600 HomoloGene: 128040 GeneCards: ORM1
Orthologs
SpeciesHumanMouse
Entrez

5004

n/a

Ensembl

ENSG00000229314

n/a

UniProt

P02763

n/a

RefSeq (mRNA)

NM_000607

n/a

RefSeq (protein)

NP_000598

n/a

Location (UCSC)Chr 9: 114.32 – 114.33 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene.[3]

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.[3]

Interactions

ORM1 has been shown to interact with Plasminogen activator inhibitor-1.[4]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000229314 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. 1 2 "Entrez Gene: ORM1 orosomucoid 1".
  4. Boncela, J; Papiewska I; Fijalkowska I; Walkowiak B; Cierniewski C S (Sep 2001). "Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type 1 and stabilizes its inhibitory activity". J. Biol. Chem. United States. 276 (38): 35305–11. doi:10.1074/jbc.M104028200. ISSN 0021-9258. PMID 11418606.

Further reading


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