Pearse is a surname. Notable people with the name include:

• Alfred Pearse (1855–1933), English cartoonist and campaigner
• Arthur Sperry Pearse (1877–1956), American botanist and zoologist
• Barbara Pearse (born 1948), British biological scientist
• Benjamin Pearse (1832–1902), Anglo-Canadian surveyor and administrator
• Cecilia, Lady Pearse (1853–1926), British writer
• Christopher Pearse Cranch (1813–1892), American writer and artist
• George Pearse (disambiguation), several people
• Guy Pearse, Australian author and environmentalist
• Isabel Pearse (1912–1999), American actress
• John Pearse (politician) (c.1760–1836), British politician and Governor of the Bank of England
• John Pearse (1939–2008), British guitarist
• Mabel Cosgrove Wodehouse Pearse (born 1872), Irish writer
• Margaret Pearse (1857–1932), Irish politician, mother of Patrick, Willie and Margaret Mary
• Margaret Mary Pearse (1878–1968), Irish politician and teacher, sister of Patrick Pearse
• Mark Guy Pearse (1842–1930), English preacher, lecturer and author
• Ormerod Pearse (1884–1953), South African cricketer
• Patrick Pearse (1879–1916), Irish teacher, barrister, poet, writer, nationalist and political activist, older brother of William Pearse
• Richard Pearse (1877–1953), New Zealand inventor
• Rupert Pearse, British physician specialising in intensive care medicine
• Samuel Pearse (1897–1919), Australian soldier and recipient of the Victoria Cross
• Samuel Herbert Pearse (born 1865), Nigerian businessman
• Susan Beatrice Pearse (1878–1980), British illustrator
• Thomas Deane Pearse (c.1738–1789), British Army officer
• Vyvyan Pearse (1891–1956), South African cricketer
• Willie Pearse (1881–1916), Irish nationalist, younger brother of Patrick Pearse

See also

• Pearce (surname)
• Pears (surname)
• Pierce (surname)
• Peirce (surname)
• Pearson (surname)