RAPGEF6
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesRAPGEF6, KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2, Rap guanine nucleotide exchange factor 6
External IDsOMIM: 610499 MGI: 2384761 HomoloGene: 22968 GeneCards: RAPGEF6
Orthologs
SpeciesHumanMouse
Entrez

51735

192786

Ensembl

ENSG00000158987

ENSMUSG00000037533

UniProt

Q8TEU7

n/a

RefSeq (mRNA)

NM_001252494
NM_001252496
NM_001252497
NM_001252498
NM_175258

RefSeq (protein)

n/a

Location (UCSC)Chr 5: 131.42 – 131.64 MbChr 11: 54.41 – 54.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rap guanine nucleotide exchange factor 6 is a protein that in humans is encoded by the RAPGEF6 gene.[5][6][7]


References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000158987 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037533 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gao X, Satoh T, Liao Y, Song C, Hu CD, Kariya Ki K, Kataoka T (Nov 2001). "Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". J Biol Chem. 276 (45): 42219–42225. doi:10.1074/jbc.M105760200. PMID 11524421.
  6. Kozlov G, Banville D, Gehring K, Ekiel I (Jul 2002). "Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions". J Mol Biol. 320 (4): 813–820. doi:10.1016/S0022-2836(02)00544-2. PMID 12095257.
  7. "Entrez Gene: RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6".

Further reading


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