RILP
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesRILP, PP10141, Rab interacting lysosomal protein
External IDsOMIM: 607848 MGI: 2144271 HomoloGene: 19596 GeneCards: RILP
Orthologs
SpeciesHumanMouse
Entrez

83547

280408

Ensembl

ENSG00000274145
ENSG00000167705

ENSMUSG00000038195

UniProt

Q96NA2

Q5ND29

RefSeq (mRNA)

NM_031430

NM_001029938

RefSeq (protein)

NP_113618

NP_001025109

Location (UCSC)Chr 17: 1.65 – 1.65 MbChr 11: 75.4 – 75.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Rab-interacting lysosomal protein is a protein that in humans is encoded by the RILP gene.[5][6]

Function

RILP, along with the GTPase RAB7 (MIM 602298), controls late endocytic transport.[supplied by OMIM][6]

Interactions

RILP (gene) has been shown to interact with RAB7A.[5][7]

References

  1. 1 2 3 ENSG00000167705 GRCh38: Ensembl release 89: ENSG00000274145, ENSG00000167705 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038195 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Cantalupo G, Alifano P, Roberti V, Bruni CB, Bucci C (February 2001). "Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes". EMBO J. 20 (4): 683–93. doi:10.1093/emboj/20.4.683. PMC 145419. PMID 11179213.
  6. 1 2 "Entrez Gene: RILP Rab interacting lysosomal protein".
  7. Caplan S, Hartnell LM, Aguilar RC, Naslavsky N, Bonifacino JS (July 2001). "Human Vam6p promotes lysosome clustering and fusion in vivo". J. Cell Biol. 154 (1): 109–22. doi:10.1083/jcb.200102142. PMC 2196876. PMID 11448994.

Further reading


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