Sofalcone
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • [5-[(3-Methylbut-2-en-1-yl)oxy]-2-((2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl)phenoxy]acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC27H30O6
Molar mass450.531 g·mol−1
3D model (JSmol)
  • CC(=CCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
  • InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)/b12-7+ ☒N
  • Key:GFWRVVCDTLRWPK-KPKJPENVSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Sofalcone (INN) is an oral gastrointestinal medication used in Japan.[1] It is a synthetic analog of sophoradin,[2] a type of natural phenol found in Sophora tonkinensis, an herb used in traditional Chinese medicine.

References

  1. "Sofalcone". drugs.com.
  2. Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R (August 1987). "Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin". Hepatogastroenterology. 34 (4): 164–70. PMID 3478294.
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