Synthetic catalytic scavenger

A Synthetic catalytic scavenger is an artificial anti-oxidant that has been demonstrated to extend cellular life. It was successful in C. elegans and was effective in rat trials.^[1] Studies have shown that synthetic catalytic scavengers have superoxide dismutase and catalase activities which prevented injuries from reactive oxygen species, helping promote the livelihood of tissues.^[2]

References

↑ Pucheu, S.; Boucher, F.; et al. (1996). "EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated iron-overloaded rat heart from functional and structural damage induced by ischemia/reperfusion". Cardiovascular Drugs and Therapy. 10 (3): 331–339. doi:10.1007/bf02627957. PMID 8877076.
↑ Doctrow, Susan R.; Huffman, Karl; et al. (28 August 2002). "Salen−Manganese Complexes as Catalytic Scavengers of Hydrogen Peroxide and Cytoprotective Agents: Structure−Activity Relationship Studies". Journal of Medicinal Chemistry. 45 (20): 4549–4558. doi:10.1021/jm020207y. PMID 12238934.

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[1] Pucheu, S.; Boucher, F.; et al. (1996). "EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated iron-overloaded rat heart from functional and structural damage induced by ischemia/reperfusion". Cardiovascular Drugs and Therapy. 10 (3): 331–339. doi:10.1007/bf02627957. PMID 8877076.

[2] Doctrow, Susan R.; Huffman, Karl; et al. (28 August 2002). "Salen−Manganese Complexes as Catalytic Scavengers of Hydrogen Peroxide and Cytoprotective Agents: Structure−Activity Relationship Studies". Journal of Medicinal Chemistry. 45 (20): 4549–4558. doi:10.1021/jm020207y. PMID 12238934.

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