TIMM10B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTIMM10B, FXC1, TIM10B, Tim9b, translocase of inner mitochondrial membrane 10 homolog B (yeast), translocase of inner mitochondrial membrane 10B
External IDsOMIM: 607388 MGI: 1315196 HomoloGene: 8142 GeneCards: TIMM10B
Orthologs
SpeciesHumanMouse
Entrez

26515

14356

Ensembl

ENSG00000132286

ENSMUSG00000089847

UniProt

Q9Y5J6

Q9WV96

RefSeq (mRNA)

NM_012192

NM_019502

RefSeq (protein)

NP_036324

Location (UCSC)Chr 11: 6.48 – 6.48 MbChr 7: 105.64 – 105.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mitochondrial import inner membrane translocase subunit Tim9 B is an enzyme that in humans is encoded by the FXC1 gene.[5][6]

FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000132286 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000089847 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Jin H, Kendall E, Freeman TC, Roberts RG, Vetrie DL (Feb 2000). "The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins". Genomics. 61 (3): 259–67. doi:10.1006/geno.1999.5966. PMID 10552927.
  6. 1 2 "Entrez Gene: FXC1 fracture callus 1 homolog (rat)".

Further reading


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