TRIM52, also known as RNF102, is a protein in the tripartite motif family. In humans, it is encoded by the gene of the same name. Knockdown of this gene induces apoptosis. This gene's overexpression has been implicated in multiple types of cancer including ovarian cancer,[1] gastric cancer,[2] and colon cancer. [3]


References

  1. ↑ Pu, Chi; Ciren, Yangla; Liu, Yun; Long, Ziwen (2021-01-01). "TRIM52 knockdown inhibits cell proliferation and induces apoptosis through activation of the STAT3 pathway in ovarian cancer1". All Life. Informa UK Limited. 14 (1): 646–656. doi:10.1080/26895293.2021.1947394. ISSN 2689-5293. S2CID 237771422.
  2. ↑ Zheng, Beiyi; Wang, Jianhua; Wang, Haozhen; Wang, Wenling; Jin, Yude (2022-06-17). "TRIM52 promotes proliferation, invasion, and migration of gastric cancer cells by regulating Wnt/β-catenin pathway". Tropical Journal of Pharmaceutical Research. African Journals Online (AJOL). 21 (5): 957–963. doi:10.4314/tjpr.v21i5.8. ISSN 1596-9827. S2CID 249968002.
  3. ↑ Guo, Yanjiao; Zhou, Yiming; Gu, Xiaodong; Xiang, Jianbin (2022). "Tripartite motif 52 (TRIM52) promotes proliferation, migration, and regulation of colon cancer cells associated with the NF-κB signaling pathway". Journal of Gastrointestinal Oncology. AME Publishing Company. 13 (3): 1097–1111. doi:10.21037/jgo-22-317. ISSN 2078-6891. PMC 9274054. PMID 35837156.
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