TRNA-guanine15 transglycosylase
Identifiers
EC no.2.4.2.48
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

TRNA-guanine15 transglycosylase (EC 2.4.2.48, tRNA transglycosylase, transfer ribonucleate glycosyltransferase, tRNA guanine15 transglycosidase, TGT, transfer ribonucleic acid guanine15 transglycosylase) is an enzyme with systematic name tRNA-guanine15:7-cyano-7-carbaguanine tRNA-D-ribosyltransferase.[1] This enzyme catalyses the following chemical reaction

guanine15 in tRNA + 7-cyano-7-carbaguanine 7-cyano-7-carbaguanine15 in tRNA + guanine

Archaeal tRNAs contain the modified nucleoside archaeosine at position 15.

References

  1. Bai Y, Fox DT, Lacy JA, Van Lanen SG, Iwata-Reuyl D (September 2000). "Hypermodification of tRNA in Thermophilic archaea. Cloning, overexpression, and characterization of tRNA-guanine transglycosylase from Methanococcus jannaschii". The Journal of Biological Chemistry. 275 (37): 28731–8. doi:10.1074/jbc.M002174200. PMID 10862614.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.