Unilateral ovarian agenesis, also known as unilateral ovarian absence (UOA), is a rare condition in an individual has one ovary instead of two not explained by previous ovariectomy. Possible causes include torsion or vascular obstruction leading to loss of one ovary, and true agenesis where the ovary never formed during development. It is much more common than having no functional ovaries (XX gonadal dysgenesis). Based on two cases reported at a Malaysian institution that performed 22,483 gynecological and obstetric surgeries, the prevalence has been estimated as 1 in 11,241. A 2023 review suggests that this is likely an underestimate since UOA is often asymptomatic and reported as an incidental finding in laparoscopic surgeries. Fertility is probably minimally affected by the condition, if at all.[1][2][3][4][5]

References

  1. ↑ Chen, H. Alexander; Grimshaw, Alyssa A.; Taylor-Giorlando, Melissa; Vijayakumar, Pavithra; Li, Dan; Margetts, Miranda; Pelosi, Emanuele; Vash-Margita, Alla (16 January 2023). "Ovarian absence: a systematic literature review and case series report". Journal of Ovarian Research. 16 (1): 13. doi:10.1186/s13048-022-01090-1. ISSN 1757-2215. PMC 9841619. PMID 36642704.
  2. ↑ Uckuyu, Ayla; Ozcimen, Emel E.; Sevinc Ciftci, F. Ceylan (2009). "Unilateral congenital ovarian and partial tubal absence: Report of four cases with review of the literature". Fertility and Sterility. 91 (3): 936.e5–936.e8. doi:10.1016/j.fertnstert.2008.09.022. PMID 18976994.
  3. ↑ Dare, F.O.; Makinde, O.O.; Makinde, O.N.; Odutayo, R. (1989). "Congenital absence of an ovary in a Nigerian woman". International Journal of Gynecology & Obstetrics. 29 (4): 377–378. doi:10.1016/0020-7292(89)90364-0. PMID 2571540. S2CID 12377327.
  4. ↑ Mylonas, I.; Hansch, S.; Markmann, S.; Bolz, M.; Friese, K. (2003). "Unilateral ovarian agenesis: report of three cases and review of the literature". Archives of Gynecology and Obstetrics. 268 (1): 57–60. doi:10.1007/s00404-002-0451-z. ISSN 1432-0711. PMID 12673478. S2CID 11857691.
  5. ↑ Tzitzimikas, S.; Fragkos, M.; Karavida, A.; Mettler, L. (2013). "Unilateral ovarian absence". Gynecological Surgery. 10 (1): 93–95. doi:10.1007/s10397-012-0773-1. ISSN 1613-2084. S2CID 1003854.
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