2017–2018: ATP and Masters debuts, first ATP win

In September 2017 he made his ATP debut at the 2017 Chengdu Open as a wildcard. In October 2017 he made his Masters debut at the Shanghai Masters as a wildcard.

In 2018, Wu recorded his first ATP win against Li Zhe at the Shanghai Masters. In the second round he won the first set against Kei Nishikori.^[7]

2019–2021: Hiatus due to injury

He did not compete from March 2019 to December 2021 due to injury.

2022: Historic major debut, top 125

In 2022, he won three Challenger titles in the United States, including back-to-back trophy runs in July in Rome, Georgia and Indianapolis. As a result, he reached the top 200 at a career-high of No. 174, on 25 July 2022.^[8] His four career total Challenger titles made him the most decorated Chinese player in the circuit's history.^[9]

At the US Open he qualified to make his Grand Slam debut.^[10] He became the first male Chinese in the Open Era to qualify at the US Open, winning his last qualifying match before Zhang Zhizhen also won his last match later in the same day.^{[11][12][13][14]} Wu won his first round match against 31st seed Nikoloz Basilashvili, becoming the first male Chinese player to win a US Open match in the Open era and a Grand Slam match in 63 years since Mei Fu Chi at Wimbledon 1959.^[15][16] He beat fellow qualifier Nuno Borges in five sets in the second round to become the first Chinese male player to reach the third round of any Grand Slam event since Kho Sin-Kie in 1946 Wimbledon. He also became the first Chinese man ever to reach the third round in the tournament history (since 1881).^[17][18] As a result, he moved 43 positions up to world No. 131 in the rankings on 12 September 2022. He then lost to world No. 1, Daniil Medvedev, in the third round.

He finished his year ranked No. 119, 1000 spots higher than his ranking at the end of the 2021 season.

2023: First Chinese ATP champion in the Open Era, top 60

Wu started his season playing the first Adelaide International, where, in qualifying, he defeated Ugo Humbert but lost to Alexei Popyrin. He received a wildcard into the 2023 Australian Open, where he lost to Corentin Moutet in the first round.^[19]

Following a final showing in the Cleveland Challenger, Wu made his debut in the top 100 at world No. 97 on 6 February 2023, becoming the second Chinese male player to do so after Zhang Zhizhen four months earlier.^[20][21]

In Dallas, Wu defeated Michael Mmoh in the first round, then claimed the biggest win of his career by defeating third seed Denis Shapovalov in the second round to reach his first ATP Tour-level quarterfinal.^[22] He then beat Adrian Mannarino to become the first Chinese player since Pan Bing in 1995 to reach an ATP Tour level semifinal, and only the second ever player from China to do so.^[23] By defeating top seed and world No. 8 Taylor Fritz in the semifinals, he became the first Chinese male ever to defeat a top 10 ranked player and to make an ATP Tour level final in the Open Era.^[24][25][26] He went one step further to win the title defeating John Isner after saving four championship points in the match, and become the first Chinese man in the Open Era to win an ATP title. In doing so, he became the highest-ranked Chinese player in the history of the ATP Rankings, and overtook Zhang to become the first Chinese player to enter the top 60 on 13 February 2023.^[26][27] He received a wildcard for the 2023 BNP Paribas Open where he defeated Jaume Munar for his first win at this tournament.^[28] At the 2023 Miami Open he recorded also his first win at this Masters against Kyle Edmund.^[1]

After losing in the first round of Barcelona and Madrid, Wu won his first match on clay by beating Richard Gasquet in Rome in 3 sets, before losing to Francisco Cerúndolo in the second round. In Geneva, he reached his first quarterfinal on clay, after beating Marc-Andrea Hüsler and Marco Cecchinato. He retired in the quarterfinals against Alexander Zverev. At the French Open, he lost to Roberto Bautista Agut in the first round. At the 2023 Wimbledon Championships, he lost to tenth seed Frances Tiafoe.

Singles

Current through the 2023 Miami Open.

Doubles

Singles: 1 (1 title)

Result	W–L	Date	Tournament	Tier	Surface	Opponent	Score
Win	1–0	Feb 2023	Dallas Open, United States	250 Series	Hard (i)	John Isner	6–7(4–7), 7–6(7–3), 7–6(14–12)

Singles: 9 (6–3)

Result	W–L	Date	Tournament	Tier	Surface	Opponent	Score
Win	1–0	Mar 2017	China F3, Anning	Futures	Clay	Danilo Petrović	6–4, 7–6(8–6)
Win	2–0	Sep 2017	Shanghai, China	Challenger	Hard	Lu Yen-hsun	7–6(8–6), 0–0 ret.
Loss	2–1	July 2018	China F10, Shenzhen	Futures	Hard	Te Rigele	6–4, 4–6, 3–6
Win	3–1	Apr 2022	M15 Orange Park, USA	World Tennis Tour	Clay	Michael Zheng	7–6(7–4), 7–5
Win	4–1	Jun 2022	Orlando, USA	Challenger	Hard	Jason Kubler	6–7(5–7), 6–4, 3–1 ret.
Win	5–1	Jul 2022	Rome, USA	Challenger	Hard (i)	Ben Shelton	7–5, 6–3
Win	6–1	Jul 2022	Indianapolis, USA	Challenger	Hard (i)	Aleksandar Kovacevic	6–7(10–12), 7–6(15–13), 6–3
Loss	6–2	Oct 2022	Seoul, South Korea	Challenger	Hard	Li Tu	6–7(5–7), 4–6
Loss	6–3	Feb 2023	Cleveland, USA	Challenger	Hard (i)	Aleksandar Kovacevic	6–3, 5–7, 6–7(2–7)

Doubles: 1 (0–1)

Result	W–L	Date	Tournament	Tier	Surface	Partner	Opponents	Score
Loss	0–1	May 2017	Spain F12, Lleida	Futures	Clay	Boris Arias	Erik Crepaldi Pascal Meis	6–7(3–7), 4–6

Singles: 1 (title)

Result	Year	Tournament	Surface	Opponent	Score
Win	2017	US Open	Hard	Axel Geller	6–4, 6–4

Doubles: 1 (title)

Result	Year	Tournament	Surface	Partner	Opponent	Score
Win	2017	US Open	Hard	Hsu Yu-hsiou	Toru Horie Yuta Shimizu	6–4, 5–7, [11–9]

Wins over top 10 players

Wu has a 1–4 (20.0%) record against players who were, at the time the match was played, ranked in the top 10.

#	Player	Rank	Event	Surface	Rd	Score	WYR
2023
1.	Taylor Fritz	8	Dallas Open, United States	Hard (i)	SF	6–7(3–7), 7–5, 6–4	97