Game 1

The A's managed only five hits off of Grimes in Game 1, but all were for extra bases and each produced a run in five different innings. Al Simmons and Mickey Cochrane hit solo home runs for the A's, helping Lefty Grove to a 5–2 win. The A's struck first in the bottom of the second when Jimmie Foxx tripled and scored on Bing Miller's sacrifice fly. The Cardinals loaded the bases in the third on three straight leadoff singles, then Taylor Douthit's lineout and Sparky Adams's sacrifice fly scored a run each. Simmons's home run in the fourth tied the game. In the sixth, Max Bishop walked with one out and scored on Foxx's double. Next inning, Mule Haas tripled with one out and scored on Joe Boley's groundout. Cochrane's eighth inning home run gave the A's their last run of the game.

Game 2

George Earnshaw allowed six hits and walked one, putting the A's ahead 2–0. The Athletics scored six runs in the first four innings to put the game out of reach. Mickey Cochrane's two-out home run in the first gave the A's their first run. After Al Simmons singled, Jimmie Foxx's RBI double made it 2–0 A's. George Watkins's home run in the second gave the Cardinals their only run of the game. In the third, Cochrane reached on an error and scored on Simmons's double. After an intentional walk, Bing Miller's RBI single made it 4–1 A's. Philadelphia added two more runs next inning on Jimmy Dykes's double.

Game 3

After the A's loaded the bases in the top of the first, Hallahan settled down and pitched a shutout. Philadelphia left a total of 11 men on base. The Cardinals scored the game's first run on Taylor Douthit's home run in the fourth, then next inning hit three consecutive one-out singles, the last of which by Charlie Gelbert scoring a run. In the seventh, Bill Shores allowed three consecutive leadoff singles, the last of which by Jimmie Wilson scoring two runs. Next inning, the Cardinals added another run off of Jack Quinn on back-to-back one-out doubles by Jim Bottomley and Chick Hafey.

Game 4

An error by Jimmy Dykes in the fourth inning allowed the Cardinals to score two runs. Haines did not allow a hit after the third inning. The A's got on the board in the first on Al Simmons's RBI single, but the Cardinals tied the game in the third when Charlie Gelbert tripled and scored on Jesse Haines's single. In the fourth, Chick Hafey hit a two-out ground rule double and scored on Dykes's error on Ray Blades's ground ball. Blades then scored on Gelbert's RBI single.

Game 5

George Earnshaw dueled Burleigh Grimes scoreless through seven innings before Lefty Grove took over for Earnshaw in the eighth. In the top of the ninth, Grimes walked Mickey Cochrane and then coughed up a home run ball to Jimmie Foxx. It must have been a patented Foxx blast, for Grimes said later, "he hit it so hard I couldn't feel sorry for myself."

Game 6

Earnshaw earned his second win on just one day of rest, pitching a five-hitter; it would be 88 years before another pitcher would start consecutive games in the postseason. Just like in Game 1, the A's seven hits came in five different innings, leading to two runs in the first and fourth innings, and single runs in the third, fifth, and sixth innings. As in Game 1, all the A's hits were extra-base hits, including home runs by Al Simmons and Jimmy Dykes.

Although the A's hit only .197 (35–for–178) in the six game set, 18 of their hits went for extra bases, outscoring the Cardinals, 21–12. St. Louis only managed a .200 batting average in the series.

The A's struck first in the first on RBI doubles by Mickey Cochrane and Bing Miller, both after walks. Simmon's home run in the third off of Syl Johnson made it 3–0 A's, then Dykes's home run after a walk in the fourth increased their lead to 5–0. The A's added to their lead next inning when Jimmie Foxx hit a leadoff double, moved to third on a bunt groundout and scored on Mule Haas's sacrifice fly. the A's scored their last run of the game in the sixth off of Jim Lindsey on Cochrane's sacrifice fly. The Cardinals scored their only run of the game on Chick Hafey's RBI double in the ninth.