RCL1
Identifiers
AliasesRCL1, RNAC, RPCL1, RNA terminal phosphate cyclase like 1
External IDsOMIM: 611405 MGI: 1913275 HomoloGene: 4217 GeneCards: RCL1
Orthologs
SpeciesHumanMouse
Entrez

10171

59028

Ensembl

ENSG00000120158

ENSMUSG00000024785

UniProt

Q9Y2P8

Q9JJT0

RefSeq (mRNA)

NM_001286699
NM_001286700
NM_001286701
NM_005772

NM_021525

RefSeq (protein)

NP_001273628
NP_001273629
NP_001273630
NP_005763

NP_067500

Location (UCSC)Chr 9: 4.79 – 4.89 MbChr 19: 29.08 – 29.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the RCL1 gene.[5]

Copy number variants to the RCL1 gene are associated with a range of neuropsychiatric phenotypes,[6] and a missense variant associated with depression.[7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000120158 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024785 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: RCL1 RNA terminal phosphate cyclase-like 1".
  6. Brownstein CA, Smith RS, Rodan LH, Gorman MP, Hojlo MA, Garvey EA, et al. (May 2021). "RCL1 copy number variants are associated with a range of neuropsychiatric phenotypes". Molecular Psychiatry. 26 (5): 1706–1718. doi:10.1038/s41380-021-01035-y. PMC 8159744. PMID 33597717.
  7. Amin N, de Vrij FM, Baghdadi M, Brouwer RW, van Rooij JG, Jovanova O, et al. (May 2018). "A rare missense variant in RCL1 segregates with depression in extended families". Molecular Psychiatry. 23 (5): 1120–1126. doi:10.1038/mp.2017.49. PMC 5984098. PMID 28322274.

Further reading


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