 | |
 | |
| Names | |
|---|---|
| Preferred IUPAC name
3-Methylpentan-3-ol | |
| Other names
3-Methyl-3-pentanol Diethyl carbinol | |
| Identifiers | |
| |
3D model (JSmol) |
|
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.000.959 |
| EC Number |
|
PubChem CID |
|
| UNII | |
CompTox Dashboard (EPA) |
|
| |
| |
| Properties | |
| C6H14O | |
| Molar mass | 102.174 g/mol |
| Appearance | colorless liquid |
| Odor | fruity |
| Density | 0.8286 g/cm3 at 20 °C |
| Melting point | −23.6 °C (−10.5 °F; 249.6 K) |
| Boiling point | 122.4 °C (252.3 °F; 395.5 K) |
| 45 g/L | |
| Solubility | miscible with ethanol, diethyl ether |
| Thermochemistry | |
Heat capacity (C) |
293.4 J·mol−1·K−1 (liquid) |
| Hazards | |
| GHS labelling: | |
  | |
| Warning | |
| H226, H302 | |
| P210, P233, P240, P241, P242, P243, P264, P270, P280, P301+P312, P303+P361+P353, P330, P370+P378, P403+P235, P501 | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
710 mg/kg rat |
| Safety data sheet (SDS) | http://www.sciencelab.com/msds.php?msdsId=9926087 |
| Related compounds | |
Related compounds |
Hexanol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
3-Methyl-3-pentanol (IUPAC name: 3-methylpentan-3-ol) is an organic chemical compound and a tertiary hexanol. It is used in the synthesis of the tranquilizer emylcamate,[2] and has similar sedative and anticonvulsant actions itself.[3]
Synthesis
It can be prepared by reacting ethylmagnesium bromide with methyl acetate in the so-called Grignard reaction using dried diethyl ether or tetrahydrofuran as solvent.
Synthesis of 3-Methyl-3-pentanol
It can be prepared also by reacting ethylmagnesium bromide with butanone in the same conditions already mentioned.
References
- ↑ Lide DR (1998). Handbook of Chemistry and Physics (87 ed.). Boca Raton, Florida: CRC Press. pp. 3–400, 5–47, 8–106. ISBN 0-8493-0594-2.
- ↑ Sittig M (1988). Pharmaceutical manufacturing encyclopedia. Vol. 2 (2 ed.). William Andrew. pp. 555–556. ISBN 978-0-8155-1144-1. Retrieved 2010-01-22.
- ↑ Brown B, Schaffarzick RW, Dreisbach RH (October 1955). "Anticonvulsant properties of certain secondary and tertiary alcohols". The Journal of Pharmacology and Experimental Therapeutics. 115 (2): 230–9. PMID 13272171.
| By consumption |
| ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary alcohols (1°) |
| ||||||||||||||||
| Secondary alcohols (2°) | |||||||||||||||||
| Tertiary alcohols (3°) |
| ||||||||||||||||
| Hydric alcohols |
| ||||||||||||||||
| Amyl alcohols | |||||||||||||||||
| Aromatic alcohols | |||||||||||||||||
| Saturated fatty alcohols | |||||||||||||||||
| Branched and unsaturated fatty alcohols |
| ||||||||||||||||
| Sugar alcohols |
| ||||||||||||||||
| Terpene alcohols |
| ||||||||||||||||
| Dialcohols | |||||||||||||||||
| Trialcohols | |||||||||||||||||
| Sterols | |||||||||||||||||
| Fluoroalcohols | |||||||||||||||||
| Preparations | |||||||||||||||||
| Reactions | |||||||||||||||||
| |||||||||||||||||
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.