Etoetonitazene
Identifiers
  • 2-[2-[[4-(2-ethoxyethoxy)phenyl]methyl]-5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC24H32N4O4
Molar mass440.544 g·mol−1
3D model (JSmol)
  • CCN(CC)CCN1C2=C(C=C(C=C2)[N+](=O)[O-])N=C1CC3=CC=C(C=C3)OCCOCC
  • InChI=1S/C24H32N4O4/c1-4-26(5-2)13-14-27-23-12-9-20(28(29)30)18-22(23)25-24(27)17-19-7-10-21(11-8-19)32-16-15-31-6-3/h7-12,18H,4-6,13-17H2,1-3H3
  • Key:NWEAJFXJKVCITM-UHFFFAOYSA-N

Etoetonitazene is a benzimidazole derivative with opioid effects, first developed in the 1950s as part of the research that led to better-known compounds such as etonitazene. It is an analogue of etonitazene where the ethoxy group has been extended to ethoxyethoxy. It is less potent than etonitazene itself, but is still a potent opioid agonist with around 50x the potency of morphine, and has been sold as a designer drug since around 2022.[1][2]

See also

References

  1. ↑ "A review of the evidence on the use and harms of 2-benzyl benzimidazole ('nitazene') and piperidine benzimidazolone ('brorphine-like') opioids" (PDF). UK: Advisory Council on the Misuse of Drugs. July 2022.
  2. ↑ Hasegawa K, Minakata K, Suzuki M, Suzuki O (July 2022). "Non-fentanyl-derived synthetic opioids emerging during recent years". Forensic Toxicology. 40 (2): 234–243. doi:10.1007/s11419-022-00624-y. PMC 9052731. PMID 36454418.



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