Dimefox
Names
IUPAC name
N-[dimethylamino(fluoro)phosphoryl]-N-methylmethanamine
Other names
TL-792[1]
T-2002[1]
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.003.706
EC Number
  • 204-076-8
KEGG
UNII
  • InChI=1S/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3 ☒N
    Key: PGJBQBDNXAZHBP-UHFFFAOYSA-N ☒N
  • InChI=1/C4H12FN2OP/c1-6(2)9(5,8)7(3)4/h1-4H3
    Key: PGJBQBDNXAZHBP-UHFFFAOYAM
  • CN(C)P(=O)(N(C)C)F
Properties
C4H12FN2OP
Molar mass 154.125 g·mol−1
Appearance colourless liquid
Density 1.11 g·mL–1
14.8 g·L–1
Vapor pressure 14663 mPa
2.28·10–8 atm·m3·mol–1[2]
Pharmacology
inhalation and dermal contact
Legal status
  • UK: Banned
  • US: Banned
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Highly Toxic
GHS labelling:
GHS06: Toxic
Danger
H300, H310
P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501
Lethal dose or concentration (LD, LC):
2 mg/kg (oral, mice)[1]
1 mg/kg (oral, rats)[1]
3 mg/kg (intravenous, rabbits)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references

Dimefox, also known as TL-792 or T-2002, is a highly toxic organophosphate insecticide. In its pure form it is a colourless liquid with a fishy odour.[3] Dimefox was first produced in 1940 by the group of Gerhard Schrader in Germany. It was historically used as a pesticide, but has been deemed obsolete or discontinued for use by the World Health Organization due to being an inhibitor of acetylcholinesterase. It is not guaranteed that all commercial use of this compound ceased, but in most countries it is no longer registered for use as a pesticide.[4] It is considered an extremely hazardous substance as defined by the United States Emergency Planning and Community Right-to-Know Act.

See also

References

  1. 1 2 3 4 5 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. 1958.
  2. ↑ "Dimefox".
  3. ↑ "IUPAC FOOTPRINT Pesticides Properties Database". Archived from the original on 2011-07-22. Retrieved 2011-04-06.
  4. ↑ the WHO recommended classification of pesticides by hazard and guidelines to classification 2009,


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