Piperocaine

Clinical data
ATC code	none
Identifiers
IUPAC name 3-(2-Methylpiperidin-1-yl)propyl benzoate
CAS Number	136-82-3 Y
PubChem CID	10782
ChemSpider	10326 N
UNII	F66XUI6GZL
ChEMBL	ChEMBL127865 N
CompTox Dashboard (EPA)	DTXSID8048315
ECHA InfoCard	100.004.784
Chemical and physical data
Formula	C16H23NO2
Molar mass	261.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1CCCCN1CCCOC(C2=CC=CC=C2)=O
InChI InChI=1S/C16H23NO2/c1-14-8-5-6-11-17(14)12-7-13-19-16(18)15-9-3-2-4-10-15/h2-4,9-10,14H,5-8,11-13H2,1H3 N Key:YQKAVWCGQQXBGW-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Piperocaine is a local anesthetic drug developed in the 1920s and used as its hydrochloride salt for infiltration and nerve blocks.

Synthesis

Synthesis:^[1] Patent:^[2]

Alkylation between 3-chloropropyl benzoate [942-95-0] (1) and Pipicoline [109-05-7] (2) provides piperocaine (3).

See also

• Hexylcaine

References

Further reading

• Tiedt TN, Albuquerque EX, Bakry NM, Eldefrawi ME, Eldefrawi AT (November 1979). "Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor". Molecular Pharmacology. 16 (3): 909–21. PMID 316855.^[1]</ref>